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Papers of the Week


Papers: 17 Sep 2022 - 23 Sep 2022


2022 Sep 20


JAMA


328


11

Editor's Pick

Effect of Roflumilast Cream vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials.

Authors

Lebwohl MG, Kircik LH, Moore AY, Gold L S, Draelos ZD, Gooderham MJ, Papp KA, Bagel J, Bhatia N, Del Rosso JQ, Ferris LK, Green LJ, Hebert AA, Jones T, Kempers SE, Pariser DM, Yamauchi PS, Zirwas M, Albrecht L, Devani AR, et al.
JAMA. 2022 Sep 20; 328(11):1073-1084.
PMID: 36125472.

Abstract

Once-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor, demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis.