News

May 31 2022
A New Neuromodulatory Device That Blocks Chronic Pain at the Source
Ultra low frequency nerve stimulation effectively blocks nerve conduction, causing a remarkable reduction in chronic pain in patients with low back pain.
news Research
May 25 2022
Neutrophils Put the Brakes on Acute Pain Becoming Chronic
Neutrophils help prevent the transition from acute to chronic pain after injury. Dampening their activity with anti-inflammatory drugs, like ibuprofen or diclofenac, can prolong pain duration.
1 Member Recommends
news Research
May 19 2022
How Does Dopamine in the Anterior Cingulate Cortex Impact Chronic Pain?
The anterior cingulate cortex drives top-down pain control via dopaminergic modulation of a subset of pyramidal cells.
1 Member Recommends
news Research
May 04 2022
The Unlikely Increase of Dopaminergic Signaling in Depression Associated With Chronic Pain
Recent work suggests that the Sp5C-LPBN-VTA pathway is activated during chronic neuropathic pain and results in the increased firing of VTA dopaminergic neurons, leading to depression-like behavior.
news Research

Papers of the Week

More

Community & Resource Updates

American Society of Pain & Neuroscience (ASPN) 2022
14 Jul 2022 to 17 Jul 2022
Miami, Florida, US

See all Meetings & Events

Postdoctoral Fellow in Pain Research
Texas A&M University College of Dentistry
Dallas, Texas, US

See all Jobs

Community Updates Lower block

Forums

Jun 30 2022
IASP 2022 World Congress on Pain Award Winners: An Interview with Lauren Heathcote
Kayt Sukel

At the IASP 2022 World Congress on Pain, taking place 19-23 September in Toronto, Canada,...

Interview
Jun 23 2022
The 2022 PRF-NAPS Correspondents Blog: Day 3
PRF Team

Five early-career pain researchers are participating in the ...

Discussion

Start a new Discussion

Recent Comments

Feb 02 2022
By: Wendy Gaultney
About: The Pain Research Forum Welcomes Gregory Carbonetti and Thanks Neil Andrews for His Outstanding Service
Thank you for everything you have done Neil. I learned so much through the...
News
Oct 26 2021
By: Matthew Sapio
About: The Pain Research Forum Welcomes Gregory Carbonetti and Thanks Neil Andrews for His Outstanding Service
Congratulations, Greg! Thanks for taking up the mantle. Good luck to Neil...
News
Sep 28 2021
By: John Quintner
About: A Neurobiological Perspective on Low Back Pain: An Interview With Ben Wand
Professor Wand, thank you for an interesting interview. Perhaps you would...
Interview
Sep 21 2021
By: Matthew Sapio
About: Cutaneous Pain in Disorders Affecting Peripheral Nerves.
This is a tour de force. I am reading it right now and I am really getting...
Paper
Aug 31 2021
By: Michael Iadarola
About: Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials.
Editor's note: Michael Iadarola is a co-author of the above journal...
Paper
Aug 13 2021
By: Bamidele Owoyele
About: The Naked Mole-Rat: A Curious Creature With Many Lessons for Pain Researchers
This is an interesting piece. One is amazed at this kind of diversity in...
News
Jul 23 2021
By: George Naratadam
About: TRP Channels and Mechanical Pain: Starring TRPC5!
Something to note: TRPC channels (and TRPC5 in particular) have been...
News
May 26 2021
By: Fanglin Lu
About: I Feel Your Pain – and Analgesia
So does it mean that there might be a confounding factor in all pain...
News
Feb 20 2021
By: Pierrick Poisbeau
About: Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents.
It's fascinating to discover that only few astrocytes in the amygdala are...
Paper
Feb 03 2021
By: Andrew Wright
About: The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines?
Thank you. I very much enjoyed the podcast; it was interesting and...
Interview
Aug 15 2020
By: John Quintner
About: A New Proposed Definition of Pain
Professor Harold Merskey, who was the chair of the original IASP...
News
Aug 12 2020
By: Eric Visser
About: A New Proposed Definition of Pain
Modified pain definition: An unpleasant sensory and emotional experience...
News
Jul 23 2020
By: John Quintner
About: A New Proposed Definition of Pain
Introducing the word "resembling" in relation to "the unpleasant sensory...
News
Jul 16 2020
By: PRF Executive Editor
About: A New Proposed Definition of Pain
The revised definition of pain has now been published in PAIN, along with...
News
May 15 2020
By: Johan Vlaeyen
About: Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
You may wish to have a look at some more recent updates of this paper: [1...
Paper
Mar 06 2020
By: Ashlie Reker
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
Editor's note: this comment is co-authored by Ashlie Reker and Steve...
Paper
Feb 24 2020
By: Steve Negus
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
An unexpected finding in this study was that CCI increased rather than...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Editor's note: This was the most popular paper on PRF over the past...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Editor's Note: This paper was the most popular paper on PRF in 2019....
Paper
Sep 30 2019
By: Mamata Tamrakar
About: A New Proposed Definition of Pain
The pain threshold for each individual differs, which makes it more...
News
Sep 30 2019
By: John Quintner
About: A New Proposed Definition of Pain
In his introductory remarks, although Murat Aydede1 mentions the...
News
Sep 30 2019
By: Marc Mathys
About: A Causal Role for Long-Term Potentiation in Chronic Pain
Wonderful paper. Have the researchers found any evidence for differences...
News
Sep 14 2019
By: Murat Aydede
About: A New Proposed Definition of Pain
The news article states: "But one thing most agree on is that the...
News
Jul 13 2019
By: Howard Fields
About: Magnitude, response, and psychological determinants of placebo effects in chronic low-back pain: a randomised, double-blinded, controlled trial.
In this elegant study, the authors compare lidocaine injection of the...
Paper
Jun 03 2019
By: Howard Fields
About: Pain Management Best Practices Inter-Agency Task Force Report: Updates, Gaps, Inconsistencies, and Recommendations. Published May 9, 2019 by the US Department of Health.
Because of the epidemic of opioid overdose and the potential contribution...
Paper

Most Popular Content

Registered Users & Community

 

 

 

PRF registered users have full access to other registered users' profiles and can contact colleagues and submit content through the site. If you are not yet registered, it's free and easy to join the only web community dedicated to pain research.

 

Becoming a PRF registered user demonstrates your support for the Pain Research Forum and will contribute to the site's long-term success.

 

NEW

SIGN UP NOW for the first of four planned data blitzes to be presented as PRF virtual seminars and hosted by the IASP Neuropathic Pain Special Interest Group (NeuPSIG)! The first data blitz takes place September 14 and will feature three talks followed by Q&A and discussion. FREE for IASP members.

 

Learn more and register for this upcoming event HERE.

 

____________________________

 

 

SUPPORTERS

PRF wishes to acknowledge and thank its 2020 supporters, including Cellectricon (virtual seminar support), the Center for Advanced Pain Studies at UT Dallas (virtual seminar support), The MAYDAY Fund (Pain Beat podcast series support), the Pfizer-Lilly Alliance (IASP PRF independently developed education series support), and the Rita Allen Foundation (PRF Correspondents program support). For more information, visit our supporters page here.

 

 

 

 

        

Announcements

The PRF Correspondents are blogging!

***Take a look at the latest blog posts from the PRF Correspondents!***

 

Visit RELIEF News Today

RELIEF News is PRF's companion site for patients and the wider public. It provides coverage of the latest in pain research for anyone interested in learning more about pain. Recent highlights include data visualizations, news, interviews and podcasts. Take a look--and sign up for the RELIEF monthly e-Newsletter as well.