News

Jun 22 2021
TRP Channels and Mechanical Pain: Starring TRPC5!
A new study uses a battery of pain models in mice to implicate TRPC5 in inflammatory mechanical and spontaneous pain; results from human tissue suggest translational potential.
news Research
Jun 22 2021
Painful Cold Sensing in Teeth: A New Role for a TRP Channel in a Well-Known Tooth Cell
New research proposes that the odontoblast, via TRPC5, serves as a primary sensory cell responsible for tooth cold pain.
news Research
Jun 15 2021
Submit Your Abstract Proposal: Data Blitz Webinar Series for IASP’s Neuropathic Pain Special Interest Group -- Deadline 1 July
Be sure to submit your abstract via IASP's online submission system by July 1.
blog Research
May 24 2021
Pain Ligand-Receptor “Interactome” Revealed
Computational tool built from existing RNA sequencing dataset to advance translational pain studies.
news Drug Development | Research

Papers of the Week

More

Community & Resource Updates

UTCSP Toronto Pain Institute 2021
16 Aug 2021 to 13 Nov 2021
Virtual
Registration Deadline:
25 Jun 2021

See all Meetings & Events

Staff Scientist Position: Cell Biology, in Vivo Physiology/Pharmacology
Yale School of Medicine, Center for Neuroscience and Regeneration Research
West Haven, Connecticut, US

See all Jobs

Community Updates Lower block

Forums

Jun 21 2021
Putting Pain Psychology Front and Center: A Podcast With Amanda Williams
Kai Karos

Editor’s note: IASP will be celebrating its 50th anniversary in 2024. Even though the anniversary is still a few years away, it already...

Interview
Jun 21 2021
IASP PRF Seminar: The Cultural Neuroscience of Pain
PRF Team

Editor’s note: This seminar is the latest event in a series of seminars launched in May 2020 to help keep the pain research community...

Webinar

Start a new Discussion

Recent Comments

May 26 2021
By: Fanglin Lu
About: I Feel Your Pain – and Analgesia
So does it mean that there might be a confounding factor in all pain...
News
Feb 20 2021
By: Pierrick Poisbeau
About: Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents.
It's fascinating to discover that only few astrocytes in the amygdala are...
Paper
Feb 03 2021
By: Andrew Wright
About: The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines?
Thank you. I very much enjoyed the podcast; it was interesting and...
Interview
Aug 15 2020
By: John Quintner
About: A New Proposed Definition of Pain
Professor Harold Merskey, who was the chair of the original IASP...
News
Aug 12 2020
By: Eric Visser
About: A New Proposed Definition of Pain
Modified pain definition: An unpleasant sensory and emotional experience...
News
Jul 23 2020
By: John Quintner
About: A New Proposed Definition of Pain
Introducing the word "resembling" in relation to "the unpleasant sensory...
News
Jul 16 2020
By: PRF Executive Editor
About: A New Proposed Definition of Pain
The revised definition of pain has now been published in PAIN, along with...
News
May 15 2020
By: Johan Vlaeyen
About: Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
You may wish to have a look at some more recent updates of this paper: [1...
Paper
Mar 06 2020
By: Ashlie Reker
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
Editor's note: this comment is co-authored by Ashlie Reker and Steve...
Paper
Feb 24 2020
By: Steve Negus
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
An unexpected finding in this study was that CCI increased rather than...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Editor's note: This was the most popular paper on PRF over the past...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Editor's Note: This paper was the most popular paper on PRF in 2019....
Paper
Sep 30 2019
By: Mamata Tamrakar
About: A New Proposed Definition of Pain
The pain threshold for each individual differs, which makes it more...
News
Sep 30 2019
By: John Quintner
About: A New Proposed Definition of Pain
In his introductory remarks, although Murat Aydede1 mentions the...
News
Sep 30 2019
By: Marc Mathys
About: A Causal Role for Long-Term Potentiation in Chronic Pain
Wonderful paper. Have the researchers found any evidence for differences...
News
Sep 14 2019
By: Murat Aydede
About: A New Proposed Definition of Pain
The news article states: "But one thing most agree on is that the...
News
Jul 13 2019
By: Howard Fields
About: Magnitude, response, and psychological determinants of placebo effects in chronic low-back pain: a randomised, double-blinded, controlled trial.
In this elegant study, the authors compare lidocaine injection of the...
Paper
Jun 03 2019
By: Howard Fields
About: Pain Management Best Practices Inter-Agency Task Force Report: Updates, Gaps, Inconsistencies, and Recommendations. Published May 9, 2019 by the US Department of Health.
Because of the epidemic of opioid overdose and the potential contribution...
Paper
Apr 01 2019
By: John Wood
About: Pain-in-a-Dish Expands the Nav1.7 Research Menu
In the accompanying paper, Bennett, Serra, and Tracey make an important...
News
Mar 29 2019
By: Howard Fields
About: Core Outcome Measures in Preclinical Assessment of Candidate Analgesics.
Negus and colleagues have provided a useful in-depth review of the broad...
Paper
Mar 14 2019
By: Markus Ploner
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
The study by Tan et al. represents a major step forward in understanding...
Paper
Jan 17 2019
By: Howard Fields
About: Hedonic drinking engages a supra-spinal inhibition of thermal nociception in adult rats.
This is an excellent paper investigating the analgesic effect of sucrose...
Paper
Nov 23 2018
By: Hiroshi Ueda
About: Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
This study seems to provide the first clinical evidence to support basic...
Paper
Oct 05 2018
By: Halina Machelska
About: Kappa Opioid Receptor Distribution and Function in Primary Afferents.
This is an interesting study confirming analgesic effects mediated by...
Paper
Aug 20 2018
By: Ru-Rong Ji
About: MicroRNA-30c-5p modulates neuropathic pain in rodents.
This is an interesting study with translational potential. The authors...
Paper

Most Popular Content

Registered Users & Community

 

 

 

PRF registered users have full access to other registered users' profiles and can contact colleagues and submit content through the site. If you are not yet registered, it's free and easy to join the only web community dedicated to pain research.

 

Becoming a PRF registered user demonstrates your support for the Pain Research Forum and will contribute to the site's long-term success.

 

 

NEW!

Get a real-life view of the ICD-11 chronic pain classification and help with our study!

An IASP Task Force created a classification of chronic pain for ICD-11. To help you use the new classification, we have developed a decision algorithm guiding through the criteria. Now we would like to invite you to be the first pain specialists to test the algorithm. Take part in our innovative study design: Using our online platform you will be able to interact with virtual patients and tell us which ICD-11 diagnoses they have. This allows you to see the new ICD-11 diagnoses at work while testing the algorithm. For each participant, we will donate a tree! Interested? Click here to learn more and get started.

.

 

 

SUPPORTERS

PRF wishes to acknowledge and thank its 2020 supporters, including Cellectricon (virtual seminar support), the Center for Advanced Pain Studies at UT Dallas (virtual seminar support), The MAYDAY Fund (Pain Beat podcast series support), the Pfizer-Lilly Alliance (IASP PRF independently developed education series support), and the Rita Allen Foundation (PRF Correspondents program support). For more information, visit our supporters page here.

 

 

 

 

        

Announcements

The PRF Correspondents are blogging!

***Take a look at the latest blog posts from the PRF Correspondents!***

 

Visit RELIEF News Today

RELIEF News is PRF's companion site for patients and the wider public. It provides coverage of the latest in pain research for anyone interested in learning more about pain. Recent highlights include data visualizations, news, interviews and podcasts. Take a look--and sign up for the RELIEF monthly e-Newsletter as well.