News

Sep 20 2021
You Feel What You Eat: ω-6 Polyunsaturated Fatty Acids Drive Painful Neuropathy in Mice
A similar mechanism may be at play in people with diabetic neuropathy, suggesting the translational potential of the new findings.
news Research
Sep 14 2021
Nociceptors Regulate the Innate and Adaptive Immune Response to Viral Infection
Sensory neurons play a role in the immune response to HSV-1 infection through effects on T cells.
news Research
Sep 07 2021
The Vitamin D-Opioid Addiction Link
A new translational study reveals a correlation between opioid use and vitamin D deficiency in humans; mouse models suggest that restoring vitamin D signaling can normalize responses to opioids and improve opioid addiction.
news Research
Aug 30 2021
Substituting Cannabidiol for Pain Medications: An Experiment Well Underway in Fibromyalgia Patients
A new survey study shows that people living with fibromyalgia are already substituting CBD for opioids and other pain drugs, despite what the clinical trial evidence says.
news Drug Development | Research

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2021 Pain in Animals Workshop (PAW)
14 Oct 2021 to 15 Oct 2021
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6 Oct 2021

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University College London
London, UK

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Sep 16 2021
A Neurobiological Perspective on Low Back Pain: An Interview With Ben Wand
Aidan Cashin

Ben Wand, PhD, is a professor in the Faculty of Medicine, Nursing and Midwifery and Health Sciences at the University of Notre Dame,...

Interview
Sep 08 2021
The PRF Virtual Correspondents Blog – Cycle 4
PRF Correspondents

Fourteen early-career pain researchers and clinicians are taking part in the fourth cycle of the...

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Recent Comments

Aug 31 2021
By: Michael Iadarola
About: Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials.
Editor's note: Michael Iadarola is a co-author of the above journal...
Paper
Aug 13 2021
By: Bamidele Owoyele
About: The Naked Mole-Rat: A Curious Creature With Many Lessons for Pain Researchers
This is an interesting piece. One is amazed at this kind of diversity in...
News
May 26 2021
By: Fanglin Lu
About: I Feel Your Pain – and Analgesia
So does it mean that there might be a confounding factor in all pain...
News
Feb 20 2021
By: Pierrick Poisbeau
About: Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents.
It's fascinating to discover that only few astrocytes in the amygdala are...
Paper
Feb 03 2021
By: Andrew Wright
About: The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines?
Thank you. I very much enjoyed the podcast; it was interesting and...
Interview
Aug 15 2020
By: John Quintner
About: A New Proposed Definition of Pain
Professor Harold Merskey, who was the chair of the original IASP...
News
Aug 12 2020
By: Eric Visser
About: A New Proposed Definition of Pain
Modified pain definition: An unpleasant sensory and emotional experience...
News
Jul 23 2020
By: John Quintner
About: A New Proposed Definition of Pain
Introducing the word "resembling" in relation to "the unpleasant sensory...
News
Jul 16 2020
By: PRF Executive Editor
About: A New Proposed Definition of Pain
The revised definition of pain has now been published in PAIN, along with...
News
May 15 2020
By: Johan Vlaeyen
About: Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
You may wish to have a look at some more recent updates of this paper: [1...
Paper
Mar 06 2020
By: Ashlie Reker
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
Editor's note: this comment is co-authored by Ashlie Reker and Steve...
Paper
Feb 24 2020
By: Steve Negus
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
An unexpected finding in this study was that CCI increased rather than...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Editor's note: This was the most popular paper on PRF over the past...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Editor's Note: This paper was the most popular paper on PRF in 2019....
Paper
Sep 30 2019
By: Mamata Tamrakar
About: A New Proposed Definition of Pain
The pain threshold for each individual differs, which makes it more...
News
Sep 30 2019
By: John Quintner
About: A New Proposed Definition of Pain
In his introductory remarks, although Murat Aydede1 mentions the...
News
Sep 30 2019
By: Marc Mathys
About: A Causal Role for Long-Term Potentiation in Chronic Pain
Wonderful paper. Have the researchers found any evidence for differences...
News
Sep 14 2019
By: Murat Aydede
About: A New Proposed Definition of Pain
The news article states: "But one thing most agree on is that the...
News
Jul 13 2019
By: Howard Fields
About: Magnitude, response, and psychological determinants of placebo effects in chronic low-back pain: a randomised, double-blinded, controlled trial.
In this elegant study, the authors compare lidocaine injection of the...
Paper
Jun 03 2019
By: Howard Fields
About: Pain Management Best Practices Inter-Agency Task Force Report: Updates, Gaps, Inconsistencies, and Recommendations. Published May 9, 2019 by the US Department of Health.
Because of the epidemic of opioid overdose and the potential contribution...
Paper
Apr 01 2019
By: John Wood
About: Pain-in-a-Dish Expands the Nav1.7 Research Menu
In the accompanying paper, Bennett, Serra, and Tracey make an important...
News
Mar 29 2019
By: Howard Fields
About: Core Outcome Measures in Preclinical Assessment of Candidate Analgesics.
Negus and colleagues have provided a useful in-depth review of the broad...
Paper
Mar 14 2019
By: Markus Ploner
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
The study by Tan et al. represents a major step forward in understanding...
Paper
Jan 17 2019
By: Howard Fields
About: Hedonic drinking engages a supra-spinal inhibition of thermal nociception in adult rats.
This is an excellent paper investigating the analgesic effect of sucrose...
Paper
Nov 23 2018
By: Hiroshi Ueda
About: Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
This study seems to provide the first clinical evidence to support basic...
Paper

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