I am a
Home I AM A Search Login

Papers of the Week


Papers: 20 Aug 2022 - 26 Aug 2022


Animal Studies, Pharmacology/Drug Development

PAIN TYPE:
Itch


2022


Front Pain Res (Lausanne)


3

An LPAR -antagonist that reduces nociception and increases pruriception.

Authors

Langedijk J, IvannaAraya E, Barroso A R, Tolenaars D, Nazaré M, Belabed H, Schoene J, Chichorro J G, Elferink R O
Front Pain Res (Lausanne). 2022; 3:963174.
PMID: 35959236.

Abstract

The G-protein coupled receptor LPAR plays a prominent role in LPA-mediated pain and itch signaling. In this study we focus on the LPAR-antagonist compound 3 (cpd3) and its ability to affect pain and itch signaling, both and .