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Papers of the Week
SUMOylation of Kir7.1 participates in neuropathic pain through regulating its membrane expression in spinal cord neurons.
Abstract
Potassium (K ) channels have been demonstrated to play a prominent involvement in nociceptive processing. Kir7.1, the newest members of the Kir channel family, has not been extensively studied in the CNS, and its function remains largely unknown. The present study investigated the role of spinal Kir7.1 in the development of pathological pain.