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Papers of the Week
Astrocyte Reactivity in Female Rats with Persistent Low Back Pain Following Spinal Mobilization.
Authors
Abstract
Low back pain (LBP) is a physiologically complex and highly disabling condition with poorly understood pathophysiology. Glial reactivity has been reported in patients with chronic LBP and astrocyte reactivity has been suggested as a potential contributor to LBP chronicity. Spinal mobilization (SM) is a non-pharmacological approach with mild to moderate efficacy in treating LBP but physiological mechanisms responsible are unknown.