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Papers of the Week
Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90 MCSs-derived microvesicles drive anti-inflammatory properties and promote cartilage regeneration after osteoarthritis.
Abstract
Osteoarthritis (OA) is a highly prevalent human degenerative joint disorder that has long plagued patients. Glucocorticoid injection into the intra-articular (IA) cavity provides potential short-term analgesia and anti-inflammatory effects, but long-term IA injections cause loss of cartilage. Synovial mesenchymal stem cells (MSCs) reportedly promote cartilage proliferation and increase cartilage content.