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Papers of the Week


Papers: 13 Feb 2021 - 19 Feb 2021


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Feb 12


Eur J Neurol

The paradigm shift of long-term treatments in migraine prevention.

Authors

Ornello R, Sacco S
Eur J Neurol. 2021 Feb 12.
PMID: 33576558.

Abstract

Monoclonal antibodies targeting calcitonin gene-related peptide (CGRP) or its receptor are a key achievement in the field of migraine prevention, being the first migraine-specific preventatives. Several characteristics distinguish monoclonal antibodies targeting the CGRP pathway from the previously available drug classes for migraine prevention, including their specificity, their monthly or quarterly subcutaneous administration, and their rapid onset of action.