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Papers of the Week


Papers: 16 Jan 2021 - 22 Jan 2021


Animal Studies


2021 Jan 13


J Allergy Clin Immunol

FcεR1 expressing nociceptors trigger allergic airway inflammation.

Authors

Crosson T, Wang J-C, Doyle B, Merrison H, Balood M, Parrin A, Pascal M, Mindt BC, Seehus CR, Ozcan A, Huang X, Semenara E, Lai N Y, Majdoubi A, Abdulnour R-EE, Rajchgot T, Rafei M, Foster SL, Thibodeau J, Fritz JH, et al.
J Allergy Clin Immunol. 2021 Jan 13.
PMID: 33453289.

Abstract

Lung nociceptor neurons amplify immune cell activity and mucus metaplasia in response to an inhaled allergen challenge in sensitized mice.