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Papers of the Week
Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain.
Authors
Abstract
The chemokine receptor, CXCR4, and the transforming growth factor-beta receptor, ALK5, both contribute to various processes associated with the sensation of pain. However, the relationship between CXCR4 and ALK5 and the possible mechanisms promoted by ALK5 in the development of pain have not been evaluated.