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Papers of the Week


Papers: 9 Nov 2019 - 15 Nov 2019

PAIN TYPE:
Migraine/Headache


2019 Dec


J Neuroophthalmol


39


4

Biochemical Modulation and Pathophysiology of Migraine.

Authors

Chan C, Wei DY, Goadsby PJ
J Neuroophthalmol. 2019 Dec; 39(4):470-479.
PMID: 31714319.

Abstract

Migraine is a common disabling neurological disorder where attacks have been recognized to consist of more than headache. The premonitory, headache, and postdromal phases are the various phases of the migraine cycle, where aura can occur before, during, or after the onset of pain. Migraine is also associated with photosensitivity and cranial autonomic symptoms, which includes lacrimation, conjunctival injection, periorbital edema, ptosis, nasal congestion, and rhinorrhoea. This review will present the current understanding of migraine pathophysiology and the relationship to the observed symptoms.