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Papers of the Week
Bladder-colon chronic cross-sensitization involves neuro-glial pathways in male mice.
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Abstract
Irritable bowel syndrome and bladder pain syndrome often overlap and are both characterized by visceral hypersensitivity. Since pelvic organs share common sensory pathways, it is likely that those syndromes involve a cross-sensitization of the bladder and the colon. The precise pathophysiology remains poorly understood.