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  • A World of Pain

    Film LIFE Before Death examines global crisis in palliative care

    Read more...

  • Moving Forward: PRF Adds New Science Advisors

    International panel will keep site on course and cruising ahead
    Read more...

  • K2P Channel Structures Unveiled

    Potassium "leak" channels are central to cell excitability and pain signaling
    Read more...

News

Feb 13 2012
A first look at two-pore-domain channels
News
Research
Feb 08 2012
Mining medical records provides a clear answer
News
Research
Feb 01 2012
International steering group offers diversity of expertise
News
People
Jan 31 2012
Documentary film LIFE Before Death premieres worldwide
News

Papers of the Week

Community & Resource Updates

 

Funding Opportunities: Upcoming Deadlines

 

29 February 2012: Letters of Intent due for RFA-HD-12-211: Tools to Enhance Studies of Glial Cell Development, Aging, Disease and Repair (R21) from the US National Institutes of Health (NIH)

 

15 March 2012: Applications due for these awards from IASP:
     IASP Research Symposium
     IASP Collaborative Research Grants
     IASP Developing Countries Collaborative Research Grants
     IASP Research Grants Funded by the Scan|Design Foundation

 

See details on all Funding Opportunities

 

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Radio Shows Available Online

 

The documentary film LIFE Before Death, which examines the global crisis in pain and palliative care, was the subject of the radio show "Aches and Gains" on 4 February and 11 February. Host Paul Christo, Johns Hopkins University School of Medicine, interviewed Mike Hill, the film's director, and Kathleen Foley, an advisor to the filmmakers and a PRF science advisor. 

 

The shows are available as podcasts at Christo’s website.

 

For more about LIFE Before Death, see PRF news story

 

 

 

Forums

Jan 27 2012

EDITOR'S NOTE: Shan Lou is a graduate student in the lab of Quifu Ma, Dana Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts...

Discussion
Dec 06 2011

EDITOR’S NOTE: In this analysis, Vincenzo Di Marzo discusses recent developments in understanding endocannabinoid actions and metabolism, and efforts...

Discussion

Recent Comments

Feb 06 2012
The PRF team attended LIFE Before Death screenings last week. We found...
News
Feb 01 2012
For colleagues in the Boston area, the Tufts Pain Research, Education and...
News
Jan 19 2012
Low-frequency stimulation (LFS) of sciatic nerve fibers was found to...
News
Jan 17 2012
By: Min Zhuo
  Spinal dorsal horn synapses are the first synapses that convey...
News
Jan 16 2012
By: Ted Price
While there is a whole body of literature on 7-transmembrane receptor (...
News
Jan 16 2012
Use-dependent long-term potentiation (LTP) of synaptic strength between...
News
Jan 06 2012
I am looking at cytokines in the CSF of people with osteoarthritis.  One...
News
Dec 22 2011
LPA appears to be essential in the estrous cycle, early pregnancy and the...
News
Dec 22 2011
Great article- thank you. I just looked up the relationship between sodium...
News
Dec 02 2011
  This is an important study, which fills in many gaps in our knowledge....
News
Nov 09 2011
By: zhi zhang
You are absolutely right. The expression of KCC2 in the NRM under...
News
Nov 05 2011
Proof of Principle in the clinic is already there with the many trials...
News
Oct 28 2011
This paper is quite complicated, but solid, all in all interesting, and...
News
Oct 26 2011
A question...Any idea why no-one ever used the King Charles Spaniel as a...
Discussion
Oct 24 2011
By: Huiyin Tu
It is hard work to understand. I have some questions:. Why were global...
Paper
Oct 21 2011
In the present study, Chen ZF and his colleagues have again successfully...
News
Oct 17 2011
Understanding epigenetic mechanisms involved in the development of chronic...
News
Oct 11 2011
A substantial proportion of patients presenting to outpatient medical...
Paper
Oct 03 2011
In this paper, Peter Smith and colleagues report that in rats, vitamin D...
Paper
Sep 23 2011
Note: This comment  is an edited version of  text  that was originally...
News
Sep 21 2011
This article is interesting in that the there are many questions that...
News
Sep 19 2011
There has been long-standing speculation that pain in preterm infants may...
News
Sep 19 2011
This exciting work indicates that modulation of HCN2 channel activity in...
Paper
Sep 12 2011
By: You Wan
HCN channels (also known as Ih or If) are important for regulating neural...
Paper
Sep 07 2011
  Is TRPV2 a receptor of painful heat? The knockouts say no.   The...
Paper

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Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our collection of topical articles on important issues in pain research--check out our inaugural articles on modeling pain in lower organisms and the role of glia in chronic pain. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes--you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.