News

Feb 01 2016
Clinical trial of FAAH inhibitor has tragic consequences
news Drug Development | Research
Jan 12 2016
CSF1 released from dorsal root ganglion neurons induces microglial activation and mechanical hypersensitivity in mouse model of neuropathic pain
news Research
Jan 04 2016
Autoantibodies from RA patients administered to mice cause pain-like behavior, independent of inflammation, through chemokine signaling
news Research
Dec 23 2015
A commentary on Lieberman and Eisenberger, 2015
blog Research

Papers of the Week

Community & Resource Updates

UCL Institute of Child Health
London, UK

Community Updates Lower block

Forums

Jan 21 2016

On January 21, Gavril Pasternak gave a talk on the promise of mu opioid receptor splice variants as a path to safer opioid...

Webinar
Oct 26 2015

On October 23, Ted Cummins gave a talk on the promise of voltage-gated sodium channels as analgesic targets. After his talk,...

Webinar

Recent Comments

Feb 01 2016
By: PRF Team
UPDATE: NEOMED has received approval from Health Canada to begin a phase...
Discussion
Jan 27 2016
I tend to agree with comments from both of the above commenters. A large...
Q & A
Jan 26 2016
The debate is still ongoing. After the criticisms by Davis et al. on...
Paper
Jan 13 2016
An elegant paper by Xu et al. reports a potential new strategy to treat...
News
Dec 23 2015
Among the three main sodium channel alpha subunits present in nociceptors...
News
Nov 19 2015
I agree with Dr. Bhagat: for local anesthetics to block voltage-gated...
Q & A
Nov 12 2015
Local anesthetics are the backbone for any dental treatment. The effects...
Q & A
Nov 02 2015
I have only had experience using three-chambered conditioned place...
Q & A
Nov 02 2015
I have done place preference experiments in both types of boxes over the...
Q & A
Oct 19 2015
This comment was co-authored by Michael Fleming, University of...
Paper
Sep 28 2015
Thanks for a great article Rosemary. This is an important topic, and one...
Discussion
Sep 18 2015
By: Ted Price
This is yet another fascinating paper from Jon Levine’s lab on...
Paper
Aug 18 2015
The range and quality of Texas pain researchers (including ex-Houstonian...
News
Aug 17 2015
The article by Martikainen et al. provides evidence to suggest enhanced...
Paper
Aug 10 2015
The authors present the first functional MRI study of spinal cord tactile...
Paper
Aug 03 2015
This comment was co-authored by David Seminowicz, University of Maryland,...
Paper
Jul 23 2015
By: Ted Price
Inceoglu and Bettaieb et al. describe a previously unrecognized induction...
News
Jun 26 2015
Since the 1970s, researchers have detected an increasing variety of neural...
News
Jun 26 2015
By: Ted Price
While ERK is a well-known contributor to pain sensitization, isoform and...
Paper
Jun 22 2015
This study by Nicol et al. uncovers a novel player, G protein receptor 84...
Paper
Jun 12 2015
In addition to this report, an elegant study co-led by Greg Neely and...
News
Jun 08 2015
This is an interesting study that is worth attention. Mindfulness...
Paper
May 29 2015
Although a number of mechanisms have been identified for the transduction...
Paper

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Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our growing collection of topical articles on important issues in pain research. Check out our articles on modeling pain in lower organisms, the role of glia in chronic pain, and transcranial magnetic stimulation. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes—you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.