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Papers of the Week


Papers: 21 Jan 2023 - 3 Feb 2023


2022 Dec 19


Neurologist

CGRP, Migraine, and Brain MRI in CADASIL: A Pilot Study.

Authors

Goldstein ED, Gopal N, Badi MK, Hodge DO, de Havenon A, Glover P, Durham PL, Huang JF, Lin MP, Baradaran H, Majersik JJ, Meschia JF
Neurologist. 2022 Dec 19.
PMID: 36729391.

Abstract

Migraine is associated with neuroimaging differences in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). However, it is unknown if migraine-related disability (MRD) or if calcitonin gene-related peptide (CGRP), a vasoactive peptide important in migraine pathology, have radiographic implications. The aims of this study were to identify whether MRD or interictal serum CGRP levels impacted neuroimaging findings for those with CADASIL.