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Papers of the Week


Papers: 21 Jan 2023 - 3 Feb 2023


2023 Jan-Jul


Neurobiol Pain


13

The autonomic and nociceptive response to acute exercise is impaired in people with knee osteoarthritis.

Authors

Bossenger NR, Lewis GN, Rice DA, Shepherd D
Neurobiol Pain. 2023 Jan-Jul; 13:100118.
PMID: 36711216.

Abstract

An acute bout of exercise typically leads to short term exercise induced hypoalgesia (EIH), but this response is more variable in many chronic pain populations, including knee osteoarthritis (OA) and fibromyalgia (FM). There is evidence of autonomic nervous system (ANS) dysfunction in some chronic pain populations that may contribute to impaired EIH, but this has not been investigated in people with knee OA. The aim of this study was to assess the acute effects of isometric exercise on the nociceptive and autonomic nervous systems in people with knee OA and FM, compared to pain-free controls.