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Papers of the Week


Papers: 22 Oct 2022 - 28 Oct 2022

PAIN TYPE:
Itch


2022 Oct 21


Cochrane Database Syst Rev


10

Topical corticosteroids for dry eye.

Authors

Liu S-H, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T
Cochrane Database Syst Rev. 2022 Oct 21; 10:CD015070.
PMID: 36269562.

Abstract

Dry eye disease (DED), arising from various etiologic factors, leads to tear film instability, ocular surface damage, and neurosensory changes. DED causes symptoms such as ocular dryness, burning, itching, pain, and visual impairment. Given their well-established anti-inflammatory effects, topical steroid preparations have been widely used as a short-term treatment option for DED. Because of potential risks of ocular hypertension, cataracts, and infections associated with the long-term use of topical steroids, published trials comparing the efficacy and safety of topical steroids (versus placebo) have mostly been of short duration (three to eight weeks).