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Papers of the Week


Papers: 10 Sep 2022 - 16 Sep 2022


Human Studies


2022 Aug 02


Ann Neurol

Brain Connectivity Predicts Chronic Pain in Acute Mild Traumatic Brain Injury.

Authors

Bosak N, Branco P, Kuperman P, Buxbaum C, Cohen R M, Fadel S, Zubeidat R, Hadad R, Lawen A, Saadon-Grosman N, Sterling M, Granovsky Y, Apkarian A V, Yarnitsky D, Kahn I
Ann Neurol. 2022 Aug 02.
PMID: 36082761.

Abstract

Previous studies have established the role of the cortico-mesolimbic and descending pain modulation systems in chronic pain prediction. Mild traumatic brain injury (mTBI) is an acute pain model where chronic pain is prevalent and complicated for prediction. In this study, we set out to study whether functional connectivity (FC) of the nucleus accumbens (NAc) and the periaqueductal gray matter (PAG) is predictive of pain chronification in early-acute mTBI.