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Papers of the Week


Papers: 20 Aug 2022 - 26 Aug 2022


2022 Aug 18


Braz J Anesthesiol

Association of low-dose naltrexone and transcranial direct current stimulation in fibromyalgia: a randomized, double-blinded, parallel clinical trial.

Authors

de Paula T M H, Castro M S, Medeiros L F, Paludo R H, Couto F F, da Costa T R, Fortes J P, de Salbego M O, Behnck G S, de Moura T A M, Tarouco M L, Caumo W, de Souza A
Braz J Anesthesiol. 2022 Aug 18.
PMID: 35988815.

Abstract

Fibromyalgia is a complex, generalized, and diffuse chronic musculoskeletal pain. Pharmacological approaches are widely used to relieve pain and increase quality of life. Low-Dose Naltrexone (LDN) was shown to increase the nociceptive threshold in patients with fibromyalgia. Transcranial Direct Current Stimulation (tDCS) is effective for pain management.