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Papers of the Week


Papers: 6 Aug 2022 - 12 Aug 2022


Human Studies


2022 Aug 06


CNS Neurol Disord Drug Targets

In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity.

Authors

Maes M, Andrés-Rodríguez L, Vojdani A, Sirivichayakul S, Barbosa DS, Kanchanatawan B
CNS Neurol Disord Drug Targets. 2022 Aug 06.
PMID: 35946099.

Abstract

A meaningful part of schizophrenia patients suffer from physiosomatic symptoms (formerly named psychosomatic) which are reminiscent of chronic fatigue syndrome and fibromyalgia (FF) and are associated with signs of immune activation and increased levels of tryptophan catabolites (TRYCATs).