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Papers of the Week


Papers: 6 Aug 2022 - 12 Aug 2022


2022 Aug 09


Pain Med

Extended Release of Bupivacaine from Temperature-Responsive Hydrogels Provides Multi-Day Analgesia for Postoperative Pain.

Authors

Abstract

A local anesthetic that provides analgesia lasting at least three days could significantly improve postoperative pain management. This study evaluated the analgesic efficacy and safety of an extended-release formulation of bupivacaine based on the injectable hydrogel carrier poly(N-isopropylacrylamide-co-dimethylbutyrolactone acrylamide-co-Jeffamine M-1000 acrylamide) (PNDJ).