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Papers of the Week


Papers: 6 Aug 2022 - 12 Aug 2022


2022


Int J Nanomedicine


17

Interaction Between Ropivacaine and a Self-Assembling Peptide: A Nanoformulation for Long-Acting Analgesia.

Authors

Peng F, Liu J, Zhang Y, Zhao G, Gong D, He L, Zhang W, Qiu F
Int J Nanomedicine. 2022; 17:3371-3384.
PMID: 35937079.

Abstract

Ropivacaine as a conventional local anesthetic has been used more and more frequently in the treatment of postoperative pain, but its analgesic effect can only last for several hours. In order to fulfill the clinic requirement for long-term analgesia, a long-acting ropivacaine nanocrystal formulation was fabricated through the interaction between ropivacaine and a self-assembling peptide.