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Papers of the Week


Papers: 30 Jul 2022 - 5 Aug 2022


2022


J Pain Res


15

Post-Inhibitory Rebound Firing of Dorsal Root Ganglia Neurons.

Authors

Zhu T, Wei S, Wang Y
J Pain Res. 2022; 15:2029-2040.
PMID: 35923842.

Abstract

In the central nervous system, post-inhibitory rebound firing (RF) may mediate overactivity of neurons under pathophysiological condition. RF is also observed in dorsal root ganglion (IRA) neurons. However, the functional significance of RF in primary sensory neurons has remained unknown. After peripheral sensory nerve/neuron injury, DRG neurons exhibit hyperexcitability. Therefore, RF may play a role in neuropathic pain.