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gy2022-1-3
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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT and opioid receptors.

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Papers: 9 Jul 2022 - 15 Jul 2022


Animal Studies

PAIN TYPE:
Migraine/Headache


2022 Jul 13


Cephalalgia


http://www.ncbi.nlm.nih.gov/pubmed/35833238?dopt=Abstract

KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT and opioid receptors.

Authors

KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT and opioid receptors.
Supronsinchai W, Hoffmann J, Akerman S, Goadsby PJ
Cephalalgia. 2022 Jul 13:3331024221112998.
PMID: 35833238.

Abstract

We aimed to examine the effects of repetitive cortical spreading depression on the responses of nociceptive trigeminal neurons with dural afferents and characterize the role of 5-HT and opioid receptors.
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