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Papers of the Week


Papers: 18 Jun 2022 - 24 Jun 2022


2022 Jun 03


Eur J Paediatr Neurol


39

Deep brain stimulation for phantom limb pain.

Authors

Pang D, Ashkan K
Eur J Paediatr Neurol. 2022 Jun 03; 39:96-102.
PMID: 35728428.

Abstract

Phantom limb pain is a rare cause of chronic pain in children but it is associated with extremely refractory pain and disability. The reason for limb amputation is often due to treatment for cancer or trauma and it has a lower incidence compared to adults. The mechanism of why phantom pain exists remains uncertain and may be a result of cortical reorganisation as well as ectopic peripheral input. Treatment is aimed at reducing both symptoms as well as managing pain related disability and functional restoration. Neuromodulatory approaches using deep brain stimulation for phantom limb pain is reserved for only the most refractory cases. The targets for brain stimulation include the thalamic nuclei and motor cortex. Novel targets such as the anterior cingulate cortex remain experimental as cases of serious adverse effects such as seziures have limited their widespread uptake. A multidisciplinary approach is crucial to successful rehabilitation using a biopsychosocial pain management approach.