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Papers of the Week


Papers: 11 Jun 2022 - 17 Jun 2022


Animal Studies


2022 Jun 11


J Neuroinflammation


19


1

Adaptation of prelimbic cortex mediated by IL-6/STAT3/Acp5 pathway contributes to the comorbidity of neuropathic pain and depression in rats.

Authors

Zhao Y-T, Deng J, Liu H-M, Wei J-Y, Fan H-T, Liu M, Xu T, Chen T-F, He J-Y, Sun W-M, Jia T-Y, Zhang X-Q, Xin W-J
J Neuroinflammation. 2022 Jun 11; 19(1):144.
PMID: 35690777.

Abstract

The adaption of brain region is fundamental to the development and maintenance of nervous system disorders. The prelimbic cortex (PrL) participates in the affective components of the pain sensation. However, whether and how the adaptation of PrL contributes to the comorbidity of neuropathic pain and depression are unknown.