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Papers of the Week
NRD.E1, an innovative non-opioid therapy for painful diabetic peripheral neuropathy – a randomised proof of concept study.
Abstract
Painful diabetic peripheral neuropathy (PDPN) affects up to 26% of patients with diabetes mellitus, with major impacts on their general health and well-being. Most available drugs fail to deliver acceptable pain reduction in the majority of patients, and are often poorly tolerated. NRD.E1 is a novel product that has shown anti-nociceptive preclinical effects and good tolerability in healthy volunteer studies.