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Papers of the Week


Papers: 16 Apr 2022 - 22 Apr 2022


Pharmacology/Drug Development


2022 Apr 18


J Headache Pain


23


1

Measuring dose-related efficacy of eptinezumab for migraine prevention: post hoc analysis of PROMISE-1 and PROMISE-2.

Authors

Apelian R, Boyle L, Hirman J, Asher D
J Headache Pain. 2022 Apr 18; 23(1):48.
PMID: 35436857.

Abstract

Eptinezumab 100 mg and 300 mg met the primary efficacy endpoint in both PROMISE clinical trials, significantly reducing frequency of monthly migraine days over Weeks 1‒12. The objective of this analysis was to assess the clinical response to eptinezumab 100 mg and 300 mg within the pivotal phase 3 PROMISE-1 and PROMISE-2 studies to potentially identify subsets of patients with meaningful differences between doses.