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Papers of the Week


Papers: 12 Feb 2022 - 18 Feb 2022


Human Studies


2022 Feb 15


Acta Neurol Scand

Long-term adherence, safety, and efficacy of repeated onabotulinumtoxinA over five years in chronic migraine prophylaxis.

Authors

Argyriou AA, Dermitzakis EV, Vlachos GS, Vikelis M
Acta Neurol Scand. 2022 Feb 15.
PMID: 35170031.

Abstract

OnabotulinumtoxinA (BoNTA) demonstrated a positive benefit-risk in chronic migraine (CM) patients in PREEMPT I and II phase III trials and many subsequent real-world studies. We herein aimed at evaluating the adherence to repeated BoNTA over a period of five years, while secondary objectives included the assessment of its long-term safety/efficacy and patients' satisfaction to treatment.