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Papers of the Week


Papers: 5 Feb 2022 - 11 Feb 2022


Pharmacology/Drug Development


2022 Jan


J Orthop Translat


32

Hype or hope of hyaluronic acid for osteoarthritis: Integrated clinical evidence synthesis with multi-organ transcriptomics.

Authors

Zhao K, Wen Y, Bunpetch V, Lin J, Hu Y, Zhang X, Xie Y, Zhang S, Hongwei O
J Orthop Translat. 2022 Jan; 32:91-100.
PMID: 35116224.

Abstract

Intra-articular injections of hyaluronic acid (HA), the United States Food and Drug Administration approved treatment and widely utilized to delay or reserve the progression of the osteoarthritis (OA) involves. However, this treatment has shown controversial results through various clinical practice guidelines and meta-analysis evaluations, warrants more advanced researches on its safety and effectiveness.