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Papers of the Week


Papers: 29 Jan 2022 - 4 Feb 2022


Human Studies

PAIN TYPE:
Migraine/Headache


2022 Feb 03


Eur J Clin Invest

Increased serum diamine oxidase activity in non-allergic patients with migraine.

Authors

García-Martín E, Navarro-Muñoz S, Amo G, Rodriguez C, Serrador M, Alonso-Navarro H, Calleja M, Turpín-Fenoll L, Recio-Bermejo M, García-Ruiz R, Millán-Pascual J, Navacerrada F, Plaza-Nieto J F, García-Albea E, Agúndez JAG, Jiménez-Jiménez F J
Eur J Clin Invest. 2022 Feb 03:e13757.
PMID: 35113457.

Abstract

Histamine has shown a possible role in the etiopathogenesis of migraine. It has been reported an association between some polymorphisms in the diamine oxidase (DAO) gene and migraine (specially in women). Two studies addressing DAO activity in migraine patients showed conflicting results. We investigated the possible relationship of serum DAO activity and histamine levels and 3 polymorphisms in the DAO gene with the risk for migraine.