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Papers of the Week


Papers: 29 Jan 2022 - 4 Feb 2022


Pharmacology/Drug Development


2022 Feb 01


Obstet Gynecol


139


2

Medical Cannabis for Gynecologic Pain Conditions: A Systematic Review.

Authors

Liang AL, Gingher EL, Coleman JS
Obstet Gynecol. 2022 Feb 01; 139(2):287-296.
PMID: 35104069.

Abstract

The endocannabinoid system is involved in pain perception and inflammation. Cannabis contains delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which are cannabinoids that bind to endocannabinoid system receptors. A fatty acid amide called palmitoylethanolamide (PEA) enhances endogenous cannabinoids. Given that use of medical cannabis is increasing, we sought to characterize patterns of cannabis use for gynecologic pain and its effectiveness as an analgesic.