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Papers of the Week
Spinal integration of hot and cold nociceptive stimuli by wide-dynamic-range neurons in anesthetized adult rats.
Abstract
Early neuronal processing of thermal noxious information relies mostly on molecular detectors of the transient receptor potential family expressed by specific subpopulation of sensory neurons. This information may converge to second-order wide-dynamic-range (WDR) neurons located in the deep layer of the dorsal horn of the spinal cord.