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Papers of the Week


Papers: 18 Dec 2021 - 24 Dec 2021


Animal Studies

PAIN TYPE:
Itch


2021 Dec 20


Stem Cell Res Ther


12


1

Multilineage-differentiating stress-enduring cells alleviate atopic dermatitis-associated behaviors in mice.

Authors

Fei WD, Wu JL, Gao MD, Wang Q, Zhao YY, Shan C, Shen Y, Chen G
Stem Cell Res Ther. 2021 Dec 20; 12(1):606.
PMID: 34930455.

Abstract

Pruritus is a recurring, long-lasting skin disease with few effective treatments. Many patients have unsatisfactory responses to currently available antipruritic treatments, and effective therapeutics are urgently needed to relieve symptoms. A previous study reported that mesenchymal stem cell (MSC)-mediated immune regulation could be used to treat skin inflammatory diseases. Multilineage-differentiating stress-enduring (Muse) cells are a new type of pluripotent stem cell that may also have the potential to treat inflammatory skin diseases.