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Papers of the Week


Papers: 11 Dec 2021 - 17 Dec 2021

RESEARCH TYPE:
Psychology


Animal Studies


2021 Jan-Dec


Mol Pain


17

The PKCγ neurons in anterior cingulate cortex contribute to the development of neuropathic allodynia and pain-related emotion.

Authors

Zhang X, Liu P, He X, Jiang Z, Wang Q, Gu N, Lu Y
Mol Pain. 2021 Jan-Dec; 17:17448069211061973.
PMID: 34898326.

Abstract

While the PKCγ neurons in spinal dorsal horn play an indispensable part in neuropathic allodynia, the exact effect of PKCγ neurons of brain regions in neuropathic pain remains elusive. Mounting research studies have depicted that the anterior cingulate cortex (ACC) is closely linked with pain perception and behavior, the present study was designed to investigate the contribution of PKCγ neurons in ACC to neuropathic allodynia and pain-related emotion in newly developed Prkcg-P2A-Tdtomato mice.