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Papers of the Week


Papers: 27 Nov 2021 - 3 Dec 2021


Animal Studies


2021 Nov 29


Mol Metab

PROTEOMIC QUANTITATIVE STUDY OF DORSAL ROOT GANGLIA AND SCIATIC NERVE IN TYPE 2 DIABETIC MICE.

Authors

Leal-Julià M, Vilches JJ, Onieva A, Verdés S, Sánchez Á, Chillón M, Navarro X, Bosch A
Mol Metab. 2021 Nov 29:101408.
PMID: 34856394.

Abstract

Peripheral neuropathy is the most common and debilitating complication of type 2 diabetes leading to sensory loss, dysautonomia, hyperalgesia and spontaneous noxious sensations. Despite clinical and economic burden of diabetic neuropathy, no effective treatment is available. Thus, more preclinical research must be conducted to gain further understanding of the aetiology of the disease and elucidate new therapeutic targets.