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Papers of the Week


Papers: 24 Jul 2021 - 30 Jul 2021


Pharmacology/Drug Development


2021 Jul 23


J Clin Anesth


75

Efficacy and adverse events of selective serotonin noradrenaline reuptake inhibitors in the management of postoperative pain: A systematic review and meta-analysis.

Authors

Schnabel A, Weibel S, Reichl SU, Meißner M, Kranke P, Zahn PK, Pogatzki-Zahn EM, Meyer-Frießem CH
J Clin Anesth. 2021 Jul 23; 75:110451.
PMID: 34311244.

Abstract

Selective-serotonin-noradrenaline-reuptake inhibitors (SSNRI) might be an interesting option for postoperative pain treatment. Objective was to investigate postoperative pain outcomes of perioperative SSNRI compared to placebo or other additives in adults undergoing surgery.