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Papers of the Week


Papers: 17 Jul 2021 - 23 Jul 2021


Animal Studies


2021


J Inflamm Res


14

Efficacy of Methotrexate on Rat Knee Osteoarthritis Induced by Monosodium Iodoacetate.

Authors

Yamanashi Y, Ohmichi M, Ohmichi Y, Ikemoto T, Arai Y-C, Maruyama Y, Otsuka S, Hirai S, Naito M, Deie M
J Inflamm Res. 2021; 14:3247-3259.
PMID: 34290513.

Abstract

To explore whether methotrexate (MTX) prevents joint destruction and improves pain-related behaviors in the acute phase of knee osteoarthritis (OA) induced by monosodium iodoacetate (MIA) in a rat model.