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Papers of the Week


Papers: 17 Jul 2021 - 23 Jul 2021


Animal Studies


2021 Jul 20


Eur J Pain

Original article: Spinal beta-amyloid1-42 acts as an endogenous analgesic peptide in CCI-induced neuropathic pain.

Authors

Abstract

The mechanism for reduced pain sensitivity associated with Alzheimer's disease (AD) has not been illustrated. We hypothesize that amyloid beta 1-42 (Aβ1-42) in the spinal cord acts as an endogenous analgesic peptide to suppress pain induced by nerve injury.