I am a
Home I AM A Search Login

Papers of the Week


Papers: 10 Jul 2021 - 16 Jul 2021


2021 Jul 13


Immunity


54


7

No pain, no gain: Sensory neurons heal a sunburn.

Authors

Flayer CH, Sokol CL
Immunity. 2021 Jul 13; 54(7):1374-1376.
PMID: 34260885.

Abstract

In a recent issue of Nature, Hoeffel et al. describe a novel pathway of sterile tissue repair utilizing a mouse model of sunburn. This wound healing pathway is coordinated by sensory neuron-derived TAFA4 that induces IL-10 production from Tim4 dermal macrophages to prevent sustained inflammation and the emergence of tissue fibrosis.