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Papers of the Week


Papers: 3 Jul 2021 - 9 Jul 2021


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Jun 29


J Clin Med


10


13

OnabotulinumtoxinA in Migraine: A Review of the Literature and Factors Associated with Efficacy.

Authors

Abstract

The efficacy of onabotulinumtoxinA (OnaB-A) as a preventative treatment for chronic migraine, emerging fortuitously from clinical observation is now supported by class one evidence and over two decades of real-world clinical data. There is still limited ability to predict a clinically meaningful response to OnaB-A for individual patients, however. This review summarises briefly the proposed mechanism of OnaB-A in chronic migraine, the literature of predictors of clinical response, and recent developments in the field.