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Papers of the Week


Papers: 26 Jun 2021 - 2 Jul 2021


Human Studies

PAIN TYPE:
Itch


2021 Jun 26


Dermatitis

Rapid Improvement of Itch Associated With Atopic Dermatitis With Abrocitinib Is Partially Independent of Overall Disease Improvement: Results From Pooled Phase 2b and 3 Monotherapy Studies.

Authors

Kim BS, Silverberg JI, Ständer S, Yosipovitch G, L Simpson E, DiBonaventura M, Kerkmann U, Farooqui SA, Biswas P, Valdez H, Cameron MC
Dermatitis. 2021 Jun 26.
PMID: 34175862.

Abstract

Itch, the most bothersome symptom in atopic dermatitis, is largely mediated by pruritogenic cytokines via Janus kinase 1 signaling in cutaneous sensory neurons.