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Papers: 19 Jun 2021 - 25 Jun 2021
PAIN TYPE:
Migraine/Headache
2021 Jun 20
Cephalalgia
Although the role of glutamate in migraine pathogenesis remains uncertain, there has been significant interest in the development of drug candidates that target glutamate receptors. Activation of trigeminovascular afferent fibers is now recognized as a crucial step to the onset of a migraine episode. New evidence suggests a dysfunction in peripheral glutamate regulation may play a role in this process.