Meloto CB, Ingelmo P, Perez E V, Pitt R, González Cárdenas V H, Mohamed N, Sotocinal SG, Bourassa V, Lima L V, Ribeiro-da-Silva A, Mogil JS, Diatchenko L
Mast cell (MC) activation could establish a positive feedback loop that perpetuates inflammation and maintains pain. Stabilizing MCs with ketotifen fumarate (KF) may disrupt this loop and relieve pain.