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Papers of the Week


Papers: 5 Jun 2021 - 11 Jun 2021


Human Studies, Pharmacology/Drug Development


2021 Jul-Aug


Pain Rep


6


2

Dissociative and analgesic properties of ketamine are independent and unaltered by sevoflurane general anesthesia.

Authors

Hahm EY, Chamadia S, Locascio JJ, Pedemonte JC, Gitlin J, Mekonnen J, Ibala R, Ethridge BR, Colon KM, Qu J, Akeju O
Pain Rep. 2021 Jul-Aug; 6(2):e936.
PMID: 34104842.

Abstract

Ketamine, an anesthetic adjunct, is routinely administered as part of a balanced general anesthetic technique. We recently showed that the acute analgesic and dissociation properties of ketamine are separable to suggest that distinct neural circuits underlie these states.