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Papers of the Week


Papers: 29 May 2021 - 4 Jun 2021


2021 May


Br J Pain


15


2

Mechanisms of pain in sickle cell disease.

Authors

Takaoka K, Cyril A C, Jinesh S, Radhakrishnan R
Br J Pain. 2021 May; 15(2):213-220.
PMID: 34055342.

Abstract

The hallmark of sickle cell disease (SCD) is acute and chronic pain, and the pain dominates the clinical characteristics of SCD patients. Although pharmacological treatments of SCD targeting the disease mechanisms have been improved, many SCD patients suffer from pain. To overcome the pain of the disease, there have been renewed requirements to understand the novel molecular mechanisms of the pain in SCD.