Chen Y, Wang Z-L, Yeo M, Zhang Q-J, López-Romero AE, Ding H-P, Zhang X, Zeng Q, Morales-Lázaro SL, Moore C, Jin Y-A, Yang H-H, Morstein J, Bortsov A, Krawczyk M, Lammert F, Abdelmalek M, Diehl A M, Milkiewicz P, Kremer AE, et al.
Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of anti-pruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus.