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Papers of the Week


Papers: 27 Mar 2021 - 2 Apr 2021


Animal Studies


2021 Mar 24


Life Sci


275

Plantar incision with severe muscle injury can be a cause of long-lasting postsurgical pain in the skin.

Authors

Yoshiyama Y, Sugiyama Y, Ishida K, Fuseya S, Tanaka S, Kawamata M
Life Sci. 2021 Mar 24; 275:119389.
PMID: 33774031.

Abstract

Although chronic local inflammation in deeper tissues after skin wound healing might produce chronification of acute postsurgical pain, its mechanisms have not been fully elucidated. We hypothesized that muscle injury and severe inflammation would prolong acute postsurgical pain by its central nervous system mechanisms.