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Papers of the Week


Papers: 20 Mar 2021 - 26 Mar 2021


2021 Mar 24


Curr Pain Headache Rep


25


5

Dual Enkephalinase Inhibitors and Their Role in Chronic Pain Management.

Authors

Southerland WA, Gillis J, Kuppalli S, Fonseca A, Mendelson A, Horine SV, Bansal N, Gulati A
Curr Pain Headache Rep. 2021 Mar 24; 25(5):29.
PMID: 33761014.

Abstract

Dual enkephalinase inhibitors (DENKIs) are pain medications that indirectly activate opioid receptors and can be used as an alternative to traditional opioids. Understanding the physiology of enkephalins and their inhibitors and the pharmacology of these drugs will allow for proper clinical application for chronic pain patients in the future.