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Papers: 27 Feb 2021 - 5 Mar 2021
Pharmacology/Drug Development
PAIN TYPE:
Migraine/Headache
2021 Mar 01
Expert Opin Pharmacother
Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that plays an essential role in the pathophysiology of migraine, a highly disabling neurovascular disorder characterized by severe headache attacks. Rimegepant is a small-molecule CGRP receptor antagonist that is approved by the FDA for the acute treatment of migraine and currently under investigation for migraine prophylaxis.