I am a
Home I AM A Search Login

Papers of the Week


Papers: 27 Feb 2021 - 5 Mar 2021


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Mar 01


Expert Opin Pharmacother

Evaluating rimegepant for the treatment of migraine.

Authors

de Vries T, Al-Hassany L, Maassen Van Den Brink A
Expert Opin Pharmacother. 2021 Mar 01.
PMID: 33648385.

Abstract

Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that plays an essential role in the pathophysiology of migraine, a highly disabling neurovascular disorder characterized by severe headache attacks. Rimegepant is a small-molecule CGRP receptor antagonist that is approved by the FDA for the acute treatment of migraine and currently under investigation for migraine prophylaxis.