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Papers of the Week


Papers: 20 Feb 2021 - 26 Feb 2021


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Feb 20


Neurol Ther

Ubrogepant for the Acute Treatment of Migraine: Pooled Efficacy, Safety, and Tolerability From the ACHIEVE I and ACHIEVE II Phase 3 Randomized Trials.

Authors

Hutchinson S, Dodick DW, Treppendahl C, Bennett NL, Yu S Y, Guo H, Trugman JM
Neurol Ther. 2021 Feb 20.
PMID: 33608814.

Abstract

Ubrogepant is an oral, small-molecule calcitonin gene-related peptide receptor antagonist approved for the acute treatment of migraine. The efficacy and safety of ubrogepant were demonstrated in two pivotal phase 3, single-attack, randomized, placebo-controlled trials (ACHIEVE I and ACHIEVE II).