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Papers of the Week


Papers: 28 Nov 2020 - 4 Dec 2020


Animal Studies


2020 Nov 24


Osteoarthritis Cartilage

NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis.

Authors

Berke IM, Jain E, Yavuz B, McGrath T, Chen L, Silva MJ, Mbalaviele G, Guilak F, Kaplan DL, Setton LA
Osteoarthritis Cartilage. 2020 Nov 24.
PMID: 33246158.

Abstract

This study aimed to examine the temporal activation of NF-κB and its relationship to the development of pain-related sensitivity and behavioral changes in a non-invasive murine knee loading model of PTOA.